Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rhoa  ras homolog family member A   (Synonyms: Arha, Arha1, Arha2, RhoA)
Results	Reference
1	J:174070 Bongmba OY, Martinez LA, Elhardt ME, Butler K, Tejada-Simon MV, Modulation of dendritic spines and synaptic function by Rac1: A possible link to Fragile X syndrome pathology. Brain Res. 2011 Jul 5;1399:79-95
1	J:282264 Chen P, Zhang T, Yuan Z, Shen B, Chen L, Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex. Mol Brain. 2019 Aug 28;12(1):74
1	J:143322 Chen Y, Stump RJ, Lovicu FJ, Shimono A, McAvoy JW, Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev Biol. 2008 Dec 1;324(1):161-76
1	J:333325 Cheng Q, Wu J, Xia Y, Cheng Q, Zhao Y, Zhu P, Zhang W, Zhang S, Zhang L, Yuan Y, Li C, Chen G, Xue B, Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Mol Brain. 2023 Feb 13;16(1):24
1	J:148225 Corbetta S, Gualdoni S, Ciceri G, Monari M, Zuccaro E, Tybulewicz VL, de Curtis I, Essential role of Rac1 and Rac3 GTPases in neuronal development. FASEB J. 2009 May;23(5):1347-57
1*	J:250125 Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, Lopez-Garcia IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM, Kctd13 deletion reduces synaptic transmission via increased RhoA. Nature. 2017 Nov 9;551(7679):227-231
1	J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579
1	J:142220 Liu N, Bezprozvannaya S, Williams AH, Qi X, Richardson JA, Bassel-Duby R, Olson EN, microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 2008 Dec 1;22(23):3242-54
1	J:167914 Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME, EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29;143(3):442-55
1	J:123400 Mitchell DC, Bryan BA, Liu JP, Liu WB, Zhang L, Qu J, Zhou X, Liu M, Li DW, Developmental expression of three small GTPases in the mouse eye. Mol Vis. 2007;13:1144-53
1	J:329931 Molla MR, Shimizu A, Komeno M, Rahman NIA, Soh JEC, Nguyen LKC, Khan MR, Tesega WW, Chen S, Pang X, Tanaka-Okamoto M, Takashima N, Sato A, Suzuki T, Ogita H, Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity. Commun Biol. 2022 Oct 7;5(1):1071
1*	J:75953 Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ, Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. Development. 2002 Apr;129(7):1705-14
1	J:176219 Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, Tsumura H, Maeda M, Nemoto N, Kawahara K, Torii T, Tanoue A, The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. J Neurosci. 2011 Aug 31;31(35):12579-92
1	J:276133 Yang CY, Yu TH, Wen WL, Ling P, Hsu KS, Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation. J Neurosci. 2019 Jun 19;39(25):4959-4975